Briefcase nr 61

Combating a killer

"Malaria is like the common cold, except that it's a killer" – MSF doctor

Every year between 19 and 21 million people fall ill with malaria in the SADC region, including over 15 million children under five years and close to 4 million pregnant women, the two most vulnerable groups. Between 200 000 and 300 000 of those infected in the region die each year

People across Africa celebrated Africa Malaria Day on
25 April 2004. The theme was ‘A Malaria-Free Future’ and the slogan was ‘Children for Children to Roll Back Malaria’. Malaria is the number-one killer of children in Africa where
a child dies of malaria every 30 seconds. The aim of
raising awareness is to increase action against malaria, thus paving the way for a malaria free future. Malaria kills approximately 2 million people a year, some 90% of them in Africa. These numbers come close to the estimated 3 million people worldwide who die of AIDS each year. Malaria is second only to AIDS as a killer disease on the continent.

Southern Africa continues to experience a chronic emergency as a result of three factors: the abnormal meteorological conditions that have occurred in recent years resulting in prolonged drought, the devastating impact of HIV/AIDS pandemic, and socio economic decline and increasing poverty. This has had an adverse effect on the southern Africa region resulting in humanitarian crisis, which has put an estimated 63% of the population at risk.

The relationship between drought and malaria is frequently misunderstood but has implications for people living in malaria areas both during and after droughts. Experience from southern Africa suggests that malaria can increase in normally stable malaria areas when they experience drought. This is because malnutrition reduces the immunity of the population. Once the rains return the risk of malaria epidemics increases significantly in areas of unstable malaria transmission due to an increase in breeding sites.

Malaria affects the health and wealth of nations and individuals alike. The level of poverty in remote rural areas and peri-urban areas varies from country to country in southern Africa, but one common consequence is the serious brain drain from public health institutions. This decreases the capacity and sustainability of national malaria control programmes in affected countries.
Malaria is both a disease of poverty and a cause of poverty. Its indirect costs include lost productivity and income associated with illness or death. The presence of malaria
in a community or country hampers individual and national prosperity. Because the high prevalence of both malaria and HIV increase the poverty and vulnerability of populations it is important to consider an integrated community disease control approach.

Both malaria and HIV/AIDS weaken the immune system. This has serious implications for people with HIV who are co-infected with malaria, particularly for children under five and pregnant women who are most vulnerable. Evidence suggests that co-infection increases the rate of progression of HIV disease, making it essential to prioritise HIV infected patients for prevention, early diagnosis and treatment of malaria. Malnutrition has a negative impact on the progression of both HIV and malaria.

Action falls far behind promises when it comes to the treatment of malaria, and debates about strategy are used as excuses for failure to provide resources. At stake are both the availability of resources and willingness to adopt new, more effective drugs to replace ones that are now ineffective. More than 600 million people face the daily threat of death from malaria because new treatments are unavailable where they live. About 75% of all malaria deaths are children and research shows that one out of five children born on the African continent will die of malaria. Several million more become seriously ill. “In many places, they are still given medicines whose effectiveness is very low and decreasing," the director general of the UN World Health Organization (WHO) stated. The United Nations has called on donor countries and pharmaceutical firms to provide the resources necessary to conquer new drug-resistant strains of the disease.

By 2005, 60% of children across African should be sleeping under safe mosquito nets, according to a target set at the Abuja summit in 2000. But many charities and other groups, including the WHO’s Roll Back Malaria Campaign, say they do not believe the targets set at that summit will be met.

As the rains intensify cases of malaria may increase. It is essential that national malaria control programmes and ministries of health put in place mechanisms and strategies to rapidly respond to epidemics. The main challenge is that chloroquine, the least expensive and most widely used anti-malarial drug, has lost its effectiveness in much of Africa. Campaigners in some parts of Africa say that western donors are ignoring DDT; one of the most effective weapons against malaria. DDT is a powerful insecticide that was widely used on crops in Europe and North America until the 1970s, but it kills birds and fish and has been banned in the US since 1972.

Since 2001 the WHO has been advocating a new plant-based treatment – Artemisinin combination therapy (ACT) – which it describes as ‘highly effective’. But at around $2 for an adult dose ACT costs 10 to 20 times as much as chloroquine. Most countries in Africa will need external funding to adopt it. The WHO estimates that global demand for ACT will soar from about 20 million adult treatments per year at present to 130 to 220 million next year. At the current price about $1 billion per year will be required to treat 60% of the affected population. Without successful implementation of ACT in the next decade, significant progress in controlling malaria will be impossible. The WHO has called on governments and pharmaceutical companies to place large orders to guarantee supplies of the treatment. "Increased demand is the main factor that will drive down prices," says the director of WHO's Roll Back Malaria campaign.

Medecins sans Frontiers has also stated that donors must stop wasting their money on drugs that don't work and help fund efforts by countries where malaria is endemic to make the switch to ACT. Endemic countries need to increase budget allocations to show that they are serious about improving malaria control. They need to provide ACT to individuals free of charge, or at an affordable price. So far, the Global Fund to Fight AIDS, Tuberculosis and Malaria has financed programmes to purchase 19 million
ACT treatments in Africa, compared with 10 000-20 000 treatments in 2001. By the end of 2004 it is anticipated that 16 African countries will have adopted ACT as their first line malaria treatment.


A Zambian child receives ACT treatment.  Ian Miller

  Key Indicators
 

Africa
90 % of all malaria deaths
Child dies every 30 seconds
75% of all deaths are children
SADC region annually
19-21 million fall sick
15, 583 260 children under five
3, 723, 440 pregnant women
200,000 - 300,000 die annually
Southern Africa
63% of population at risk
ACT treatment US $2 for adult dose
$1 billion per year will be required to provide 60 % of the affected population

Focus on Africa Malaria Day 2004

Africa and the malaria initiative

Nothing to celebrate on Africa Malaria Day

UN urges donors, drug firms to fund anti-malaria fight  

UN uses atomic technology to fight malaria

Campaign grows for Malaria drug

More than 600 million people urgently need effective malaria treatment

Celebrities lend their voices to children's fight against malaria

Malaria action at issue

Campaign grows for malaria drug

Malaria one of biggest killers in sub-Saharan Africa

New hope to beat killer disease in Zambia

Rolling back malaria in Zambia

50 000 Zambians die of malaria 

Malaria cases in Zambia treble over 23 years

Mozambique battles malaria

 Malaria death toll still high in Zimbabwe

Four and a half million cases of malaria in 2003

Mozambique battles malaria, country's third biggest killer

Malaria kills 50,000 Zambians in 23 years

Better harvests improve sub-Saharan Africa's food supply  

Documents

Scaling up home-based management of malaria

Children and malaria

Communication and advocacy guidelines for national malaria control programme

Community and household assessment of malaria prevention in eastern Zambia 

Malaria and HIV co-infections

Malaria epidemics: forecasting, prevention, early detection and control

Malaria in Africa

Malaria in urban and peri-urban areas in sub-Saharan Africa

Malaria prevention - Lessons learned

Strengthening health research in the developing world

Population data and malaria control

Mapping and Malaria

Links

Children for Children to Roll Back Malaria WHO/AFRO

ACT Now, An International Symposium on Malaria MSF

Malaria in southern Africa

UNICEF/UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases

MalariaNet

Nature Medicine - Special Focus Malaria

Roll Back Malaria – A Global Partnership

Southern Africa Malaria Control

WHO/OMS Malaria  

SAHIMS is a project of the United Nations Office for the Coordination of Humanitarian Affairs (OCHA)
Johannesburg, 7 May 2004

All external and original contents will open in a new window.
SAHIMS.net does not endorse external contents, nor is responsible for their availability.